Journal: Investigative Ophthalmology & Visual Science

Article Title: Enhancing Retinal Endothelial Glycolysis by Inhibiting UCP2 Promotes Physiologic Retinal Vascular Development in a Model of Retinopathy of Prematurity

doi: 10.1167/iovs.19-26553

Figure Lengend Snippet: Intraperitoneal genipin inhibits retinal UCP2, increases retinal Glut1, and reduces AVA of OIR pups. Western blots of (A, B) UCP2 and (C, D) Glut1 in retinas, and (E, F) AVA of p14 OIR pups received intraperitoneal injections of genipin or control from p3 to p14. (A, C) Representative gel images. (B, D) Quantification of densitometry. (E) Representative flat mount images. (F) quantification of AVA; *P < 0.05, **P < 0.01 versus. Control; n = 5–6 for Western blots and n = 14–16 for AVA.

Article Snippet: A mixed effects linear regression model was used to statistically analyze data collected from OIR rats for AVA and IVNV using STATA-14 software (StataCorp LLC, College Station, TX, USA).

Techniques: Western Blot

Journal: Investigative Ophthalmology & Visual Science

Article Title: Enhancing Retinal Endothelial Glycolysis by Inhibiting UCP2 Promotes Physiologic Retinal Vascular Development in a Model of Retinopathy of Prematurity

doi: 10.1167/iovs.19-26553

Figure Lengend Snippet: Intraperitoneal genipin to reduce AVA reduces intravitreal neovascularization. (A) and (B) IVNV at p18 of OIR pups received intraperitoneal injections of genipin or control from p3 to p14. (A) Representative flat mount images and (B) quantification of IVNV; *P < 0.05 versus Control. Scale bar: 990 μm. (C, D) IVNV at p18 of OIR pups treated with control or genipin from p14 to p18. (C) Representative flat mount images and (D) quantification of IVNV. Scale bar: 990 μm, n = 3–16.

Article Snippet: A mixed effects linear regression model was used to statistically analyze data collected from OIR rats for AVA and IVNV using STATA-14 software (StataCorp LLC, College Station, TX, USA).

Techniques:

Journal: Investigative Ophthalmology & Visual Science

Article Title: Enhancing Retinal Endothelial Glycolysis by Inhibiting UCP2 Promotes Physiologic Retinal Vascular Development in a Model of Retinopathy of Prematurity

doi: 10.1167/iovs.19-26553

Figure Lengend Snippet: Intraperitoneal genipin increases retinal function. Ganzfeld ERG of (A) a-wave amplitude and (B) b-wave amplitudes in p26 RA and OIR pups after overnight dark adaptation and treatment with control or genipin from p3 to p13 (*P < 0.05, ***P < 0.001 versus RA/Control; †† P < 0.01, ††† P < 0.001 versus OIR/Control; n = 4–6 for ERG and n = 11 for AVA and IVNV); and quantification of (C) AVA and (D) IVNV of OIR pups at p26 treated with control or genipin from p3 to p13.

Article Snippet: A mixed effects linear regression model was used to statistically analyze data collected from OIR rats for AVA and IVNV using STATA-14 software (StataCorp LLC, College Station, TX, USA).

Techniques:

Journal: Scientific Reports

Article Title: First Person Perspective of Seated Participants Over a Walking Virtual Body Leads to Illusory Agency Over the Walking

doi: 10.1038/srep28879

Figure Lengend Snippet: Mixed effects logistic regression of the questionnaire responses.

Article Snippet: We use mixed effects logistic regression (Stata 14 function ‘meologit’) with random effects over the individuals, and with robust standard errors (to take account of possible violations of the model assumptions).

Techniques: